Session: CIE-20 SEIKM: Advanced Manufacturing for Bioeconomy and Circular Economy

Paper Number: 143710

143710 - A Basic Formal Ontology-Based Ontological Modeling for Plan and Occurrence, a Biomanufacturing Process Verification Use Case 

In this study, we explore the application of the Counterpart Relation (CR) ontology approach, focusing on the complex case study of a biomanufacturing process. This paper presents an ongoing phase of a project. Originating from a comparative analysis of ontology approaches, CR was selected for its ability to facilitate and smooth interplay between digital and physical artifacts. Our research extends the use of the CR approach beyond its previously documented applications by employing it to construct a comprehensive ontology for a fed-batch production bioreactor operation.

Utilizing a set of competency questions allows CR to illustrate its ability to simplify the complexity inherent in constructing SPARQL queries and to facilitate rapid identification of critical biomanufacturing parameters. Importantly, this analysis is enriched by incorporating knowledge graphs, which serve not only facilitate a richer semantic understanding of data but also promote a collaborative ecosystem where information is interconnected and readily accessible. The results of our study not only demonstrate the CR approach’s ability to handle a more intricate biomanufacturing process but also further validate its effectiveness in bridging the gap between digital planning and physical execution in biomanufacturing environments. The findings also offer insights into the future of data integration and management within bioinformatics, highlighting the role of ontologies in advancing biomanufacturing processes through improved data interoperability and streamlined query mechanisms.

Presenting Author: Dusan Sormaz Ohio University

Presenting Author Biography: Dr. Dušan N. Šormaz is a Professor Emeritus of Industrial and Systems Engineering at Ohio University, Athens, USA. Dr. Dušan N. Šormaz’s principal research interests are in the application of knowledge-based systems in manufacturing including Ontologies, Simulation, Additive Manufacturing, Process Planning, and Semantic Data Integration.
Šormaz has organized several international conferences, he was the General Chair of the 28th International Conference on Flexible Automation and Intelligent Manufacturing, FAIM2018 in Columbus, and the Plenary Speaker Chair of the International Conference on Production Research, ICPR25 in Chicago 2019.
He is a member of the board of the International Foundation for Production Research (IFPR) since 2019 and a member of the editorial board of the International Journal of Industrial Engineering and Management (IJIEM) since 2012. He is a member of the Industrial Ontology Foundry (IOF) and the Chair of its Production Planning and Scheduling working group.

Authors:

Dusan Sormaz Ohio University
Saruda Seeharit Ohio University
Boonserm Kulvatunyou National Institute of Standards and Technology
Milos Drobnjakovic National Institute of Standards and Technology